Researchers Left To Guess at Outcomes of Most Cancer Clinical Trials
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منابع مشابه
Researchers left to guess at outcomes of most cancer clinical trials.
M edical literature, in general, and clinical trials of depression and cardiovascular disease, in particular, suffer from selective publication — studies published in journals tend to be overwhelmingly positive. But the situation for cancer clinical trials has not been clear. Some small studies have hinted at publication bias, but now that a public clinical trial registry exists, two researcher...
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In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2009
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djn495